For a better understanding of the mechanisms by which IR modulates T-cell activation and alters functional properties...Ionizing irradiation stimulates adhesion of peripheral blood lymphocytes (PBL). Grade 3–4 diarrhoea was more common in those Recent data, however, indi...Malignant gliomas exhibit a high intrinsic resistance against stimuli triggering apoptotic cell death. Professor: 201 Composites Manufacturing Science Laboratory: 302-831-8702 gillespi@udel.edu: James Glancey Professor: 315 Spencer Lab: 302-831-0712 jglancey@udel.edu: Jill Higginson Professor: 201B Spencer Lab/STAR: 302-831-6622 higginso@udel.edu: M. Zubaer Hossain Assistant Professor: 229 … In: Journal of the European Ceramic Society, (9), 29. pp. Western immune blots (A) and quantification (B) of Jurkat cells 48 h after irradiation with a dose of 1.25 and 2 Gy using an anti-CD25 antibody. In the present study, three different techn...Introduction: Definitive chemoradiation (CRT) followed by high-dose-rate (HDR) brachytherapy (BT) represents state-of-the-art treatment for locally-advanced cervical cancer. was feasible and led to more patients achieving a pathological complete response than In this retrospective study the expression of Hsp70 was determined in relation to tumor-infiltrating CD56⁺ NK cells in formalin-fixed paraffin embedded (FFPE) tumor specimens of patients with S...Background: In the present study we aimed to investigate the clinical relevance of Plk3 expression and phosphorylation of caspase-8 at T273 in patients with anal squamous cell carcin...Upon interaction of the CD95 receptor with its ligand, sequential association of the adaptor molecule FADD (MORT1), pro-forms of caspases-8/10, and the caspase-8/10 regulator c-FLIP leads to the formation of a death-inducing signaling complex. (B, upper panel) Coomassie-stained regrown colonies of SKOV-3 cells treat...Blocking mitotic exit sensitizes patient-derived primary ovarian cancer cells to paclitaxel. (C) Cell viability was determined...Apoptosis in ovarian cancer cells following drug treatment. Theoretische und dogmatische Grundzüge, 2. The endothelium is constantly exposed to mechanical forces caused by blood flow, and...Background and purpose During my studies I was working as a research scholar in the group of Prof. Messing at Penn State and Prof. Gauckler at ETH. The development and pre-clinical testing of novel therapeutic...Background: Definitive chemoradiotherapy (CRT) is the primary treatment for non-metastatic anal squamous cell carcinoma (ASCC). Moreover, a number of distinct mechanisms have been described regarding the modulation of tumor cell respo...Vismodegib, an inhibitor of the Hedgehog signaling pathway, is an approved drug for monotherapy in locally advanced or metastatic basal cell carcinoma (BCC). Dislocation-mediated functionality in oxides; Lead-free piezoceramics (new hard and soft materials) Lead-free antiferroelectrics for energy storage; Mecha Department of Radiotherapy and Oncology, University of Frankfurt, Frankfurt, Germany. The basic principles of radiation physics and treat...We examined (a) the expression of the antioxidative factor glutathione peroxidase (GPx) and the transcription factor nuclear factor E2-related factor 2 (Nrf2) following low-dose X-irradiation in endothelial cells (ECs) and (b) the impact of reactive oxygen species (ROS) and Nrf2 on functional properties of ECs to gain further knowledge about the an...Exploring the immunological and molecular basis of Radon in therapeutic application.Join ResearchGate to find the people and research you need to help your work.Only verified researchers can join ResearchGate and send messages to other members.University students and faculty, institute members, and independent researchersTechnology or product developers, R&D specialists, and government or NGO employees in scientific rolesHealth care professionals, including clinical researchersJournalists, citizen scientists, or anyone interested in reading and discovering researchSorry, you need to be a researcher to join ResearchGate.Due to our privacy policy, only current members can send messages to people on ResearchGate.© 2008-2020 ResearchGate GmbH. The proliferative activity of primary human fibroblasts over a period of 4 days is depicted.Peripheral blood leukocytosis and neutrophilia reflect cancer inflammation and have been proposed as prognostic immunological biomarkers in various malignancies. I received my PhD in 2018 in the group of Prof. Rödel at TU Darmstadt working together with Dr. Koruza on functional polycrystalline ceramic materials. The IC50 for single/ combinatorial treatments...proTAME decreases the viability of mitotically arrested SKOV-3 cells and sensitizes cells to paclitaxel.

(A) Following the incubation with single (3 nM paclitaxel, 20 nM BI6727, 10 μM proTAME), double, or triple agents for 48 hours and subsequent release into fresh medium for 6 days, metaphase spreads of treated SKOV-3 cells were prepared, and the chromosomes were stained with H...Proliferative activity of primary human cells following drug treatment. Six cisplatin- and six...Synopsis of the introductory paragraph of the DEGRO consensus S2e-guideline recommendations for the radiotherapy of benign disorders, including physical principles, radiobiological mechanisms, and radiogenic risk. end of 1:n-Block addresses. received fluorouracil chemoradiotherapy. HSF1 (heat shock factor 1) acts as transcription factor upstream of HSP70 and the HSP70 co-chaperone BAG3 that is overexpressed in glioblastoma. Telephone: +49 69 6301; Fax: [---]* E-mail: claus.roedel at kgu.de; URL: [---]* end of 1:1-Block address contact public-contact.

Herta Müller, novelist and Nobel Prize in Literature (2009) (Professor); Gerhard Ertl, physicist and Nobel Prize in Chemistry (2007) (Professor); Reinhard Selten, economist and Nobel Memorial Prize in Economic Sciences (1994) (Professor); Ernst Ruska, physicist and Winner of Nobel Prize in Physics (1986) (Professor); Ulrich Cubasch, climate scientist and co-author of reports by the … Each bar graph represents the mean value ± SEM (n=3).

and oxaliplatin during chemoradiotherapy and in 127 (20%) of 624 patients who actually CURRENT RESEARCH TOPICS. The phase III German CAO/ARO/AIO-04 trial showed, that the addition of oxaliplatin increased treatment efficacy in terms of early …

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